Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Sden_2162Homogentisate 1,2-dioxygenase. (386 aa)    
Predicted Functional Partners:
Sden_2163
4-hydroxyphenylpyruvate dioxygenase.
 
 0.999
Sden_2591
Maleylacetoacetate isomerase.
  
 
 0.981
Sden_2595
Phenylalanine 4-hydroxylase.
 
  
 0.937
Sden_2592
Fumarylacetoacetate (FAA) hydrolase.
 
  
 0.879
Sden_2637
Fumarylacetoacetate (FAA) hydrolase.
  
  
 0.820
Sden_2594
Pterin-4-alpha-carbinolamine dehydratase.
  
  
 0.771
Sden_2914
Conserved hypothetical protein.
   
    0.569
Sden_1668
Aminotransferase.
  
  
 0.502
Sden_1750
Aminotransferase.
  
  
 0.502
Sden_2247
methylglutaconyl-CoA hydratase.
   
  
 0.489
Your Current Organism:
Shewanella denitrificans
NCBI taxonomy Id: 318161
Other names: S. denitrificans OS217, Shewanella denitrificans OS217, Shewanella denitrificans str. OS217, Shewanella denitrificans strain OS217
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.