node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sden_0332 | Sden_1782 | Sden_0332 | Sden_1782 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase, RecQ family. | 0.922 |
Sden_0332 | Sden_2505 | Sden_0332 | Sden_2505 | ATP-dependent DNA helicase RecQ. | SMC protein-like protein. | 0.747 |
Sden_0332 | polA | Sden_0332 | Sden_3620 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.880 |
Sden_0332 | recA | Sden_0332 | Sden_1208 | ATP-dependent DNA helicase RecQ. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.841 |
Sden_0332 | recD | Sden_0332 | Sden_2353 | ATP-dependent DNA helicase RecQ. | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.752 |
Sden_0332 | sbcD | Sden_0332 | Sden_2506 | ATP-dependent DNA helicase RecQ. | Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.874 |
Sden_0332 | topA | Sden_0332 | Sden_2328 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.924 |
Sden_0332 | topB | Sden_0332 | Sden_2400 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.883 |
Sden_0332 | xni | Sden_0332 | Sden_2558 | ATP-dependent DNA helicase RecQ. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.810 |
Sden_1782 | Sden_0332 | Sden_1782 | Sden_0332 | ATP-dependent DNA helicase, RecQ family. | ATP-dependent DNA helicase RecQ. | 0.922 |
Sden_1782 | Sden_2505 | Sden_1782 | Sden_2505 | ATP-dependent DNA helicase, RecQ family. | SMC protein-like protein. | 0.743 |
Sden_1782 | polA | Sden_1782 | Sden_3620 | ATP-dependent DNA helicase, RecQ family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.880 |
Sden_1782 | recA | Sden_1782 | Sden_1208 | ATP-dependent DNA helicase, RecQ family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.841 |
Sden_1782 | recD | Sden_1782 | Sden_2353 | ATP-dependent DNA helicase, RecQ family. | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.752 |
Sden_1782 | sbcD | Sden_1782 | Sden_2506 | ATP-dependent DNA helicase, RecQ family. | Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.841 |
Sden_1782 | topA | Sden_1782 | Sden_2328 | ATP-dependent DNA helicase, RecQ family. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.924 |
Sden_1782 | topB | Sden_1782 | Sden_2400 | ATP-dependent DNA helicase, RecQ family. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.919 |
Sden_1782 | xni | Sden_1782 | Sden_2558 | ATP-dependent DNA helicase, RecQ family. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.810 |
Sden_2505 | Sden_0332 | Sden_2505 | Sden_0332 | SMC protein-like protein. | ATP-dependent DNA helicase RecQ. | 0.747 |
Sden_2505 | Sden_1782 | Sden_2505 | Sden_1782 | SMC protein-like protein. | ATP-dependent DNA helicase, RecQ family. | 0.743 |