Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Sden_2575Cobalamin synthesis protein, P47K. (364 aa)    
Predicted Functional Partners:
rpsN
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
 
 
 0.887
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.846
Sden_0528
Periplasmic solute binding protein.
  
  
 0.841
rpmB
LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.812
dksA
RNA polymerase-binding, DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
  
  
 0.802
Sden_2389
Hypothetical protein.
  
  
 0.775
rpmG
LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family.
  
  
 0.721
Sden_2576
DEAD/DEAH box helicase-like protein; Belongs to the DEAD box helicase family.
   
   0.571
hisI
phosphoribosyl-ATP pyrophosphatase / phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.567
Sden_0036
Carbonic anhydrase, family 3.
  
  
 0.561
Your Current Organism:
Shewanella denitrificans
NCBI taxonomy Id: 318161
Other names: S. denitrificans OS217, Shewanella denitrificans OS217, Shewanella denitrificans str. OS217, Shewanella denitrificans strain OS217
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