| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Sden_1620 | Sden_2448 | Sden_1620 | Sden_2448 | Peptidase M22, glycoprotease. | Translation factor SUA5; Belongs to the SUA5 family. | 0.622 |
| Sden_1620 | Sden_3209 | Sden_1620 | Sden_3209 | Peptidase M22, glycoprotease. | Protein of unknown function UPF0079. | 0.981 |
| Sden_1620 | tsaC | Sden_1620 | Sden_0029 | Peptidase M22, glycoprotease. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.667 |
| Sden_1620 | tsaD | Sden_1620 | Sden_2830 | Peptidase M22, glycoprotease. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.976 |
| Sden_2448 | Sden_1620 | Sden_2448 | Sden_1620 | Translation factor SUA5; Belongs to the SUA5 family. | Peptidase M22, glycoprotease. | 0.622 |
| Sden_2448 | Sden_3209 | Sden_2448 | Sden_3209 | Translation factor SUA5; Belongs to the SUA5 family. | Protein of unknown function UPF0079. | 0.622 |
| Sden_2448 | tsaD | Sden_2448 | Sden_2830 | Translation factor SUA5; Belongs to the SUA5 family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.639 |
| Sden_3208 | Sden_3209 | Sden_3208 | Sden_3209 | N-acetylmuramoyl-L-alanine amidase. | Protein of unknown function UPF0079. | 0.855 |
| Sden_3208 | alr | Sden_3208 | Sden_0522 | N-acetylmuramoyl-L-alanine amidase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.518 |
| Sden_3208 | hflX | Sden_3208 | Sden_3204 | N-acetylmuramoyl-L-alanine amidase. | GTP-binding protein, HSR1-related; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.617 |
| Sden_3208 | miaA | Sden_3208 | Sden_3206 | N-acetylmuramoyl-L-alanine amidase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.859 |
| Sden_3208 | mutL | Sden_3208 | Sden_3207 | N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.870 |
| Sden_3208 | nnrD | Sden_3208 | Sden_2235 | N-acetylmuramoyl-L-alanine amidase. | Protein of unknown function UPF0031; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.626 |
| Sden_3209 | Sden_1620 | Sden_3209 | Sden_1620 | Protein of unknown function UPF0079. | Peptidase M22, glycoprotease. | 0.981 |
| Sden_3209 | Sden_2448 | Sden_3209 | Sden_2448 | Protein of unknown function UPF0079. | Translation factor SUA5; Belongs to the SUA5 family. | 0.622 |
| Sden_3209 | Sden_3208 | Sden_3209 | Sden_3208 | Protein of unknown function UPF0079. | N-acetylmuramoyl-L-alanine amidase. | 0.855 |
| Sden_3209 | alr | Sden_3209 | Sden_0522 | Protein of unknown function UPF0079. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.681 |
| Sden_3209 | hflX | Sden_3209 | Sden_3204 | Protein of unknown function UPF0079. | GTP-binding protein, HSR1-related; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.606 |
| Sden_3209 | miaA | Sden_3209 | Sden_3206 | Protein of unknown function UPF0079. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.843 |
| Sden_3209 | mutL | Sden_3209 | Sden_3207 | Protein of unknown function UPF0079. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.831 |