STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfri_0446PFAM: protein of unknown function DUF484; KEGG: son:SO4307 hypothetical protein. (246 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
    0.932
xerC
Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
    0.800
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
    0.678
Sfri_0703
KEGG: son:SO1172 DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
  
     0.658
Sfri_0448
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO4305 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein.
 
    0.627
Sfri_2933
PFAM: MucB/RseB family protein; KEGG: son:SO1344 sigma-E factor regulatory protein RseB.
  
     0.604
Sfri_0443
KEGG: son:SO4310 hypothetical protein.
       0.589
bamE
SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.530
Sfri_0259
Conserved hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
     0.526
Sfri_2977
KEGG: son:SO1303 hypothetical protein.
  
     0.501
Your Current Organism:
Shewanella frigidimarina
NCBI taxonomy Id: 318167
Other names: S. frigidimarina NCIMB 400, Shewanella frigidimarina NCIMB 400, Shewanella frigidimarina str. NCIMB 400, Shewanella frigidimarina strain NCIMB 400
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