| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Sfri_0984 | Sfri_1396 | Sfri_0984 | Sfri_1396 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.997 |
| Sfri_0984 | Sfri_2242 | Sfri_0984 | Sfri_2242 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate lyase apoprotein; PFAM: aminotransferase, class IV; KEGG: son:SO2615 4-amino-4-deoxychorismate lyase. | 0.926 |
| Sfri_0984 | Sfri_2558 | Sfri_0984 | Sfri_2558 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PFAM: dihydroneopterin aldolase; KEGG: son:SO2921 D-erythro-7,8-dihydroneopterin triphosphate epimerase. | 0.748 |
| Sfri_0984 | Sfri_2989 | Sfri_0984 | Sfri_2989 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: son:SO1292 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.992 |
| Sfri_0984 | Sfri_2990 | Sfri_0984 | Sfri_2990 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.986 |
| Sfri_0984 | Sfri_3279 | Sfri_0984 | Sfri_3279 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | 0.999 |
| Sfri_0984 | folE | Sfri_0984 | Sfri_3162 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PFAM: GTP cyclohydrolase I; KEGG: son:SO4254 GTP cyclohydrolase I. | 0.911 |
| Sfri_0984 | folE-2 | Sfri_0984 | Sfri_3834 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PFAM: GTP cyclohydrolase I; KEGG: son:SO4254 GTP cyclohydrolase I. | 0.911 |
| Sfri_0984 | ftsH | Sfri_0984 | Sfri_0983 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.796 |
| Sfri_0984 | glmM1 | Sfri_0984 | Sfri_0985 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.803 |
| Sfri_1396 | Sfri_0984 | Sfri_1396 | Sfri_0984 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
| Sfri_1396 | Sfri_2558 | Sfri_1396 | Sfri_2558 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | PFAM: dihydroneopterin aldolase; KEGG: son:SO2921 D-erythro-7,8-dihydroneopterin triphosphate epimerase. | 0.473 |
| Sfri_1396 | Sfri_2989 | Sfri_1396 | Sfri_2989 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: son:SO1292 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.518 |
| Sfri_1396 | Sfri_2990 | Sfri_1396 | Sfri_2990 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.615 |
| Sfri_1396 | Sfri_3279 | Sfri_1396 | Sfri_3279 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | 0.680 |
| Sfri_1396 | folE | Sfri_1396 | Sfri_3162 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | PFAM: GTP cyclohydrolase I; KEGG: son:SO4254 GTP cyclohydrolase I. | 0.576 |
| Sfri_1396 | folE-2 | Sfri_1396 | Sfri_3834 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | PFAM: GTP cyclohydrolase I; KEGG: son:SO4254 GTP cyclohydrolase I. | 0.576 |
| Sfri_2242 | Sfri_0984 | Sfri_2242 | Sfri_0984 | Aminodeoxychorismate lyase apoprotein; PFAM: aminotransferase, class IV; KEGG: son:SO2615 4-amino-4-deoxychorismate lyase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.926 |
| Sfri_2558 | Sfri_0984 | Sfri_2558 | Sfri_0984 | PFAM: dihydroneopterin aldolase; KEGG: son:SO2921 D-erythro-7,8-dihydroneopterin triphosphate epimerase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.748 |
| Sfri_2558 | Sfri_1396 | Sfri_2558 | Sfri_1396 | PFAM: dihydroneopterin aldolase; KEGG: son:SO2921 D-erythro-7,8-dihydroneopterin triphosphate epimerase. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.473 |