Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Sfri_1900Transcriptional regulator, DeoR family protein; PFAM: putative sugar-binding domain protein; KEGG: pha:PSHAa1504 transcriptional regulator. (320 aa)    
Predicted Functional Partners:
Sfri_1899
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pha:PSHAb0206 putative unknown enzyme.
 
     0.924
Sfri_1903
PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase rossman, N-terminal domain protein; KEGG: pha:PSHAb0208 D-mannonate oxidoreductase.
 
   
 0.692
Sfri_1901
KEGG: pha:PSHAb0207 putative nucleoside transport protein.
 
     0.671
Sfri_2960
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pha:PSHAb0228 putative ABC-type transport system, permease component.
  
    0.516
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
   
 0.462
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.437
Sfri_2959
KEGG: pha:PSHAb0229 putative ABC-type transport system, periplasmic component.
  
     0.410
Your Current Organism:
Shewanella frigidimarina
NCBI taxonomy Id: 318167
Other names: S. frigidimarina NCIMB 400, Shewanella frigidimarina NCIMB 400, Shewanella frigidimarina str. NCIMB 400, Shewanella frigidimarina strain NCIMB 400
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