| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Sfri_0002 | Sfri_1285 | Sfri_0002 | Sfri_1285 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: son:SO1644 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. | 0.996 |
| Sfri_0002 | Sfri_1964 | Sfri_0002 | Sfri_1964 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | 0.814 |
| Sfri_0002 | Sfri_2629 | Sfri_0002 | Sfri_2629 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: son:SO1820 DNA polymerase II. | 0.963 |
| Sfri_0002 | polA | Sfri_0002 | Sfri_3943 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.990 |
| Sfri_0002 | recA | Sfri_0002 | Sfri_1062 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.945 |
| Sfri_1285 | Sfri_0002 | Sfri_1285 | Sfri_0002 | KEGG: son:SO1644 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.996 |
| Sfri_1285 | Sfri_1964 | Sfri_1285 | Sfri_1964 | KEGG: son:SO1644 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | 0.570 |
| Sfri_1285 | polA | Sfri_1285 | Sfri_3943 | KEGG: son:SO1644 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.765 |
| Sfri_1285 | recA | Sfri_1285 | Sfri_1062 | KEGG: son:SO1644 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.659 |
| Sfri_1963 | Sfri_1964 | Sfri_1963 | Sfri_1964 | Putative prophage repressor; PFAM: peptidase S24, S26A and S26B; KEGG: son:SOA0013 umuD protein; Belongs to the peptidase S24 family. | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | 0.975 |
| Sfri_1963 | Sfri_1965 | Sfri_1963 | Sfri_1965 | Putative prophage repressor; PFAM: peptidase S24, S26A and S26B; KEGG: son:SOA0013 umuD protein; Belongs to the peptidase S24 family. | Hypothetical protein. | 0.483 |
| Sfri_1963 | recA | Sfri_1963 | Sfri_1062 | Putative prophage repressor; PFAM: peptidase S24, S26A and S26B; KEGG: son:SOA0013 umuD protein; Belongs to the peptidase S24 family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.939 |
| Sfri_1964 | Sfri_0002 | Sfri_1964 | Sfri_0002 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.814 |
| Sfri_1964 | Sfri_1285 | Sfri_1964 | Sfri_1285 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | KEGG: son:SO1644 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. | 0.570 |
| Sfri_1964 | Sfri_1963 | Sfri_1964 | Sfri_1963 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | Putative prophage repressor; PFAM: peptidase S24, S26A and S26B; KEGG: son:SOA0013 umuD protein; Belongs to the peptidase S24 family. | 0.975 |
| Sfri_1964 | Sfri_1965 | Sfri_1964 | Sfri_1965 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | Hypothetical protein. | 0.483 |
| Sfri_1964 | Sfri_2629 | Sfri_1964 | Sfri_2629 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: son:SO1820 DNA polymerase II. | 0.817 |
| Sfri_1964 | Sfri_2712 | Sfri_1964 | Sfri_2712 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | Transcriptional regulator Ada / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: son:SO3127 Ada regulatory protein, putative. | 0.625 |
| Sfri_1964 | Sfri_3452 | Sfri_1964 | Sfri_3452 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | KEGG: son:SOA0013 umuD protein; Belongs to the peptidase S24 family. | 0.568 |
| Sfri_1964 | lexA | Sfri_1964 | Sfri_0260 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.557 |
