Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Sfri_1986TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tcx:Tcr_0379 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor. (307 aa)    
Predicted Functional Partners:
Sfri_2505
PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: pha:PSHAa1150 response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase).
 
  
 0.917
Sfri_3607
Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: vvy:VVA0651 GGDEF family protein.
  
   0.800
Sfri_2965
Diguanylate cyclase/phosphodiesterase / diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: ilo:IL1784 disrupted signaling protein (xGGDEF and EAL domains).
  
    0.796
Sfri_3909
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: ilo:IL0935 signaling protein with a sensor domain, HAMP, GGDEF and EAL domains.
  
   0.795
Sfri_1987
PFAM: alpha/beta hydrolase fold; KEGG: bsu:BG12442 similar to hydrolase.
  
    0.782
Sfri_2171
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO2507 GGDEF domain protein.
  
    0.780
Sfri_3756
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO4116 MSHA biogenesis protein MshH.
  
  
 0.753
Sfri_2300
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO1387 HD domain protein.
 
  
 0.721
Sfri_1266
PFAM: CBS domain containing protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: mag:amb0553 response regulator.
 
 0.693
Sfri_1371
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: pha:PSHAa1795 hypothetical protein.
  
    0.693
Your Current Organism:
Shewanella frigidimarina
NCBI taxonomy Id: 318167
Other names: S. frigidimarina NCIMB 400, Shewanella frigidimarina NCIMB 400, Shewanella frigidimarina str. NCIMB 400, Shewanella frigidimarina strain NCIMB 400
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