STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfri_2019PFAM: UspA domain protein; KEGG: son:SO2355 universal stress protein family. (309 aa)    
Predicted Functional Partners:
Sfri_2018
Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: son:SO2356 electron transport regulator a.
 
  
 0.680
Sfri_2492
PFAM: protein of unknown function DUF1414; KEGG: son:SO2176 hypothetical protein; Belongs to the UPF0352 family.
  
     0.665
Sfri_0996
TPR repeat-containing protein; May be involved in cell division.
  
     0.656
rraB
Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.656
Sfri_2475
PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein.
  
     0.655
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.654
seqA
seqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.606
Sfri_2491
PFAM: 37kDa nucleoid-associated protein; KEGG: son:SO2177 hypothetical protein.
  
     0.585
Sfri_1481
PFAM: protein of unknown function DUF413; KEGG: son:SO2201 hypothetical protein.
  
     0.583
dsbB
Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
  
     0.578
Your Current Organism:
Shewanella frigidimarina
NCBI taxonomy Id: 318167
Other names: S. frigidimarina NCIMB 400, Shewanella frigidimarina NCIMB 400, Shewanella frigidimarina str. NCIMB 400, Shewanella frigidimarina strain NCIMB 400
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.