STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slyXPFAM: SlyX family protein; KEGG: son:SO1063 SlyX protein; Belongs to the SlyX family. (70 aa)    
Predicted Functional Partners:
rraB
Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.756
Sfri_3358
KEGG: son:SO3938 hypothetical protein.
  
     0.736
Sfri_2475
PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein.
  
     0.726
Sfri_2949
PFAM: Hpt domain protein; KEGG: son:SO1327 sensor histidine kinase-related protein.
  
     0.722
Sfri_2934
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
     0.697
lapA
Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.691
Sfri_3239
PFAM: WD-40 repeat protein; KEGG: son:SO1064 hypothetical WD domain protein.
       0.681
Sfri_1588
PFAM: protein of unknown function DUF991; KEGG: son:SO2182 hypothetical protein.
  
     0.678
proQ
ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
     0.674
zapC
Protein of unknown function DUF1379; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.667
Your Current Organism:
Shewanella frigidimarina
NCBI taxonomy Id: 318167
Other names: S. frigidimarina NCIMB 400, Shewanella frigidimarina NCIMB 400, Shewanella frigidimarina str. NCIMB 400, Shewanella frigidimarina strain NCIMB 400
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.