Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IO99_01720Stage IV sporulation protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)    
Predicted Functional Partners:
IO99_01725
Chemotaxis protein CheY; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.965
IO99_01630
Stage III sporulation protein AE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.851
IO99_01625
Stage III sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.849
IO99_01610
Stage III sporulation protein AA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.841
IO99_01640
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.836
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.831
IO99_01735
Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.825
IO99_01615
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.806
IO99_14425
Stage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.805
IO99_14420
Stage V sporulation protein AC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.804
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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