Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IO99_03230Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)    
Predicted Functional Partners:
IO99_03235
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.929
IO99_03240
Catabolite gene activator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.891
IO99_15550
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.523
IO99_14895
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.471
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.465
pyrD
Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate.
  
    0.464
pyrF
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
    0.459
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
    0.430
IO99_12230
gltD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.423
IO99_10545
Uracil transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.414
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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