Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IO99_03495Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)    
Predicted Functional Partners:
IO99_03500
methylcobamide:CoM methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
 
    0.957
IO99_03505
Cobalamin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.946
IO99_03510
Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.923
IO99_03515
methylcobamide:CoM methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
 
    0.911
IO99_07250
methylcobamide:CoM methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.807
IO99_08680
Cobalamin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.800
IO99_07970
Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.797
IO99_08675
Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.787
IO99_15335
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.549
IO99_01030
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.493
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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