Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IO99_04005Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)    
Predicted Functional Partners:
IO99_03990
Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.958
IO99_03995
Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.958
IO99_04000
Methionine ABC transporter substrate-binding protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.957
IO99_04015
L-erythro-3,5-diaminohexanoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.917
IO99_04020
3-keto-5-aminohexanoate cleavage protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.884
IO99_04010
Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.881
IO99_04025
3-aminobutyryl-CoA ammonia lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.877
IO99_14720
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.521
pdxT
Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.408
pdxS
Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.408
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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