STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IO99_08910HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)    
Predicted Functional Partners:
IO99_08915
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.797
IO99_12685
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.797
IO99_08920
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.795
IO99_08925
Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
cpsB
Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.658
IO99_08905
tRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.621
IO99_10050
Riboflavin kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family.
   
 0.543
IO99_15460
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.541
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.535
IO99_08930
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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