Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IO99_16005MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)    
Predicted Functional Partners:
IO99_16000
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
  
  
 0.751
IO99_14530
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
  
  
 0.503
hypA-2
Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
       0.466
IO99_15985
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.466
IO99_15990
Ni/Fe hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.466
IO99_15995
Ni/Fe hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.466
IO99_03035
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.422
IO99_04375
Glycine/betaine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.422
IO99_04370
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.407
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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