Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IO99_16645Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)    
Predicted Functional Partners:
IO99_15335
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.827
IO99_16640
3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
    0.802
IO99_10510
Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
      0.740
IO99_01030
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.535
IO99_16635
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.532
IO99_12300
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
     
  0.471
IO99_10535
Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.463
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
    
  0.458
gcvPA
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
     
  0.456
gcvPB
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
     
  0.456
Your Current Organism:
Clostridium sulfidigenes
NCBI taxonomy Id: 318464
Other names: C. sulfidigenes, Clostridium sulfidigenes Sallam and Steinbuchel 2009, DSM 18982, strain SGB2
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