STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS4828Uncharacterized protein. (837 aa)    
Predicted Functional Partners:
DME_LOCUS3093
Uncharacterized protein.
 
 0.991
DME_LOCUS3228
Uncharacterized protein.
 
 0.988
DME_LOCUS8078
Uncharacterized protein.
  
 0.984
DME_LOCUS2853
4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family.
  
 
 0.970
DME_LOCUS6776
Pyruvate carboxyltransferase domain-containing protein.
 
 0.964
DME_LOCUS2435
SCP2 domain-containing protein.
  
 0.956
DME_LOCUS6142
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 0.948
DME_LOCUS3894
Uncharacterized protein.
   
 0.944
DME_LOCUS9744
Uncharacterized protein.
   
 0.944
DME_LOCUS2258
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.943
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.