STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS5671Uncharacterized protein; Belongs to the DEAD box helicase family. (404 aa)    
Predicted Functional Partners:
DME_LOCUS962
Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.
   
 0.943
DME_LOCUS3860
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.922
DME_LOCUS877
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
 0.902
DME_LOCUS41
WD_REPEATS_REGION domain-containing protein.
   
 0.888
DME_LOCUS5387
CP-type G domain-containing protein.
  
 0.883
DME_LOCUS1709
Uncharacterized protein.
   
 0.879
DME_LOCUS2021
TOG domain-containing protein.
   
 0.871
DME_LOCUS8814
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.866
DME_LOCUS3164
Uncharacterized protein.
   
 0.860
DME_LOCUS8481
RRM domain-containing protein.
    
 0.859
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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