STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS7509Uncharacterized protein. (271 aa)    
Predicted Functional Partners:
DME_LOCUS1253
Uncharacterized protein.
  
 
 0.877
DME_LOCUS7093
Uncharacterized protein.
    
 0.769
DME_LOCUS7095
MGS domain-containing protein.
    
 0.769
DME_LOCUS8901
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.717
DME_LOCUS6701
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.686
DME_LOCUS8779
Uncharacterized protein.
    
 
 0.674
DME_LOCUS8780
TYR_PHOSPHATASE_2 domain-containing protein.
    
 
 0.674
DME_LOCUS5085
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.657
DME_LOCUS5232
Pribosyltran domain-containing protein.
  
 
 0.646
DME_LOCUS2365
Uncharacterized protein.
  
 
  0.635
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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