STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS8781Uncharacterized protein. (131 aa)    
Predicted Functional Partners:
DME_LOCUS10042
Death domain-containing protein.
    
 0.995
DME_LOCUS2046
THOC2_N domain-containing protein.
   
 0.995
DME_LOCUS86
WD_REPEATS_REGION domain-containing protein.
   
 0.995
DME_LOCUS4864
Uncharacterized protein.
   
 0.994
DME_LOCUS5430
WD_REPEATS_REGION domain-containing protein.
    
 0.993
DME_LOCUS899
Uncharacterized protein.
   
 0.982
DME_LOCUS8481
RRM domain-containing protein.
   
 0.919
DME_LOCUS3176
Uncharacterized protein.
   
 0.919
DME_LOCUS3062
Uncharacterized protein.
   
 0.898
DME_LOCUS9190
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
   
 
 0.860
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.