STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS1558Cyclin_C domain-containing protein; Belongs to the cyclin family. (287 aa)    
Predicted Functional Partners:
DME_LOCUS6626
AAA domain-containing protein.
   
 0.989
DME_LOCUS6955
Uncharacterized protein.
   
 0.970
DME_LOCUS2364
Uncharacterized protein; Belongs to the cyclin family.
   
0.964
DME_LOCUS5028
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.955
DME_LOCUS211
Uncharacterized protein.
   
 0.954
DME_LOCUS6355
HORMA domain-containing protein.
   
 
 0.953
DME_LOCUS5118
MCM domain-containing protein; Belongs to the MCM family.
   
 0.951
DME_LOCUS1695
Uncharacterized protein.
    
 0.950
DME_LOCUS9915
Protein kinase domain-containing protein.
   
 0.940
DME_LOCUS6946
WD_REPEATS_REGION domain-containing protein.
   
 0.939
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.