STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS9797Uncharacterized protein. (598 aa)    
Predicted Functional Partners:
DME_LOCUS7389
CPSF_A domain-containing protein.
    
 0.985
DME_LOCUS710
Cullin_Nedd8 domain-containing protein.
    
 0.870
DME_LOCUS711
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.870
DME_LOCUS7699
Uncharacterized protein.
    
 0.860
DME_LOCUS3807
PCI domain-containing protein.
    
 0.800
DME_LOCUS5693
MPN domain-containing protein.
    
 0.786
DME_LOCUS4869
MPN domain-containing protein.
    
 0.781
DME_LOCUS2729
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
     
 0.776
DME_LOCUS3730
WD_REPEATS_REGION domain-containing protein.
    
 0.763
DME_LOCUS8842
Zf-rbx1 domain-containing protein.
    
  0.757
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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