STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS3039DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (179 aa)    
Predicted Functional Partners:
DME_LOCUS8614
Thymidylat_synt domain-containing protein.
 
 0.999
DME_LOCUS703
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.953
DME_LOCUS5514
Thymidylate_kin domain-containing protein.
    
 0.950
DME_LOCUS9673
ATP-grasp domain-containing protein.
  
 
 0.949
DME_LOCUS9942
dUTPase domain-containing protein.
  
 
 0.946
DME_LOCUS7644
Uncharacterized protein.
  
 
 0.945
DME_LOCUS9546
CMP/dCMP-type deaminase domain-containing protein.
  
 
 0.945
DME_LOCUS1530
Mur_ligase_M domain-containing protein.
    
 0.935
DME_LOCUS6496
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
    
 0.931
DME_LOCUS8460
Uncharacterized protein.
  
 
 0.917
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.