STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS4159ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (155 aa)    
Predicted Functional Partners:
DME_LOCUS1964
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.893
DME_LOCUS7930
Uncharacterized protein.
    
 0.887
DME_LOCUS9380
Uncharacterized protein.
   
 0.884
DME_LOCUS1856
Uncharacterized protein.
   
 0.884
DME_LOCUS10148
Uncharacterized protein.
   
 0.869
DME_LOCUS2626
WD_REPEATS_REGION domain-containing protein.
   
 
 0.801
DME_LOCUS1252
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.752
DME_LOCUS8099
Uncharacterized protein; Belongs to the actin family.
   
 0.736
DME_LOCUS9282
Uncharacterized protein; Belongs to the actin family.
   
 0.718
DME_LOCUS1552
Profilin; Belongs to the profilin family.
   
 0.712
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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