STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DME_LOCUS6000TGF_BETA_2 domain-containing protein. (325 aa)    
Predicted Functional Partners:
DME_LOCUS10349
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.992
DME_LOCUS2307
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.992
DME_LOCUS2982
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.985
DME_LOCUS7701
Mothers against decapentaplegic homolog.
    
 0.943
DME_LOCUS9895
DAN domain-containing protein.
    
 0.922
DME_LOCUS882
Uncharacterized protein.
    
 
 0.887
DME_LOCUS7905
Mothers against decapentaplegic homolog.
  
 
 0.856
DME_LOCUS455
Mothers against decapentaplegic homolog.
  
 
 0.851
DME_LOCUS7729
MH2 domain-containing protein.
  
 
 0.848
DME_LOCUS8076
Mothers against decapentaplegic homolog.
  
 
 0.845
Your Current Organism:
Dracunculus medinensis
NCBI taxonomy Id: 318479
Other names: D. medinensis, Guinea worm, Guinea worm disease nematode, dracunculiasis worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.