Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pden_0191PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cme:CMP184C hypothetical protein, conserved Pfam: Glyoxalase. (137 aa)    
Predicted Functional Partners:
Pden_0192
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: tma:TM1724 3-oxoacyl-(acyl carrier protein) reductase.
  
   0.719
Pden_0189
PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rpe:RPE_1982 TRAP C4-dicarboxylate transport system permease DctM subunit.
       0.531
Pden_0190
PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: mlo:mll5171 hypothetical protein.
       0.531
Pden_0188
PFAM: regulatory proteins, IclR; KEGG: bps:BPSS2127 IclR transcriptional regulator protein.
       0.520
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.491
Pden_0193
TRAP dicarboxylate transporter- DctP subunit; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
       0.437
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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