STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_0436PFAM: protein of unknown function DUF179; KEGG: sil:SPO0296 putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (190 aa)    
Predicted Functional Partners:
Pden_0951
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 0.900
Pden_1384
Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 0.900
Pden_1802
KEGG: rsp:RSP_6229 hypothetical protein.
   
 0.900
Pden_4377
Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.900
Pden_0510
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
  
  
 0.757
Pden_0437
KEGG: rde:RD1_3420 hypothetical protein.
       0.733
ccmG
Periplasmic protein thiol--disulfide oxidoreductase DsbE; Required for disulfide bond formation in some periplasmic proteins. Also acts as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur; Belongs to the thioredoxin family. DsbE subfamily.
   
 
 0.690
Pden_2023
PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: rsp:RSP_0725 thioredoxin, thioldisulfide interchange protein.
   
 
 0.687
Pden_3020
PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mca:MCA1549 succinate dehydrogenase, hydrophobic membrane anchor protein, putative.
  
    0.676
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
  
 0.632
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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