Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pden_0791TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sil:SPO0517 HAD-superfamily hydrolase, subfamily IA, variant 1. (220 aa)    
Predicted Functional Partners:
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
  
 
0.923
Pden_0617
KEGG: rsp:RSP_2504 phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase.
  
  
 
0.920
Pden_1700
PFAM: ribulose bisphosphate carboxylase, small chain; KEGG: rpa:RPA1560 ribulose-bisphosphate carboxylase small chain.
    
 0.906
Pden_4037
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: jan:Jann_3650 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
 0.906
Pden_4398
PFAM: FAD linked oxidase domain protein; KEGG: sit:TM1040_2501 FAD linked oxidase-like.
    
 0.905
Pden_4399
PFAM: FAD linked oxidase domain protein; KEGG: rsp:RSP_1020 putative glycolate oxidase subunit protein.
    
 0.905
cbbL
Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.
    
 0.904
Pden_4397
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: sil:SPO3480 glycolate oxidase, iron-sulfur subunit.
    
 0.904
Pden_1941
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: jan:Jann_0915 glycolate reductase.
    
  0.902
crcB
Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
  
 0.895
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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