STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttcAPP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (297 aa)    
Predicted Functional Partners:
Pden_0409
PFAM: aminotransferase, class V; KEGG: ret:RHE_PE00221 hypothetical protein.
    
 0.903
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.788
Pden_0874
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
       0.773
rpmH
PFAM: ribosomal protein L34; KEGG: rsp:RSP_1059 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
     
 0.744
Pden_0040
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: bmb:BruAb1_0211 thiamine biosynthesis ThiS.
  
 
 0.686
yidC
Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
     
 0.633
engB
Small GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
     
 0.615
Pden_0876
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: rde:RD1_1456 EAL domain protein.
       0.599
Pden_0037
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sit:TM1040_3654 UBA/ThiF-type NAD/FAD binding fold.
  
 
 0.571
Pden_0878
PFAM: MOSC domain containing protein; KEGG: rsp:RSP_1065 hypothetical protein.
       0.563
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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