node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0902 | Pden_1273 | Pden_0902 | Pden_1273 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | 0.734 |
Pden_0902 | Pden_2571 | Pden_0902 | Pden_2571 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.482 |
Pden_0902 | Pden_2608 | Pden_0902 | Pden_2608 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.603 |
Pden_0902 | Pden_3908 | Pden_0902 | Pden_3908 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | 0.694 |
Pden_0902 | Pden_3909 | Pden_0902 | Pden_3909 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.710 |
Pden_0902 | lpxA | Pden_0902 | Pden_3907 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.685 |
Pden_0902 | lpxC | Pden_0902 | Pden_4486 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.643 |
Pden_0902 | lpxD | Pden_0902 | Pden_1241 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.732 |
Pden_0902 | lpxK | Pden_0902 | Pden_2094 | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.680 |
Pden_1273 | Pden_0902 | Pden_1273 | Pden_0902 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease. | 0.734 |
Pden_1273 | Pden_2093 | Pden_1273 | Pden_2093 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase-like protein; KEGG: rsp:RSP_1461 putative 3-deoxy-D-manno-octulosonic-acid transferase. | 0.948 |
Pden_1273 | Pden_2571 | Pden_1273 | Pden_2571 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.974 |
Pden_1273 | Pden_2608 | Pden_1273 | Pden_2608 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.840 |
Pden_1273 | Pden_3908 | Pden_1273 | Pden_3908 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | 0.760 |
Pden_1273 | Pden_3909 | Pden_1273 | Pden_3909 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.831 |
Pden_1273 | lpxA | Pden_1273 | Pden_3907 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.806 |
Pden_1273 | lpxC | Pden_1273 | Pden_4486 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.809 |
Pden_1273 | lpxD | Pden_1273 | Pden_1241 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.833 |
Pden_1273 | lpxK | Pden_1273 | Pden_2094 | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.868 |
Pden_2093 | Pden_1273 | Pden_2093 | Pden_1273 | 3-deoxy-D-manno-octulosonic-acid transferase-like protein; KEGG: rsp:RSP_1461 putative 3-deoxy-D-manno-octulosonic-acid transferase. | PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 putative lipid A biosynthesis lauroyl acyltransferase. | 0.948 |