STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_1659Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_3512 periplasmic sensor signal transduction histidine kinase. (459 aa)    
Predicted Functional Partners:
Pden_1661
PFAM: Propeptide, PepSY amd peptidase M4; KEGG: rsp:RSP_3510 hypothetical protein.
 
  
 0.970
Pden_1660
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rsp:RSP_3511 two component transcriptional regulator, winged helix family family.
 
 
 0.963
Pden_3891
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.888
Pden_1311
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mes:Meso_0894 two component transcriptional regulator, winged helix family.
 
 0.826
Pden_1585
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mes:Meso_0894 two component transcriptional regulator, winged helix family.
 
 0.822
Pden_1604
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sme:SMb20020 putative pyruvate dehydrogenase E1 component,alpha and beta subunits protein.
   
 0.650
Pden_3049
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: aeh:Mlg_2596 dehydrogenase, E1 component.
   
 0.650
Pden_4096
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; KEGG: sil:SPO1679 DNA-binding response regulator CtrA.
 
 
 0.626
Pden_4325
Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sil:SPO1953 phosphate regulon transcriptional regulatory protein PhoB.
 
 
 0.570
Pden_3566
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bja:blr6651 two-component response regulator.
 
 
 0.562
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.