STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
betITranscriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. (189 aa)    
Predicted Functional Partners:
Pden_1899
PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc02737 putative glycine betaine-binding ABC transporter protein.
 
     0.897
Pden_1897
PFAM: aldehyde dehydrogenase; KEGG: rsp:RSP_2183 betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.862
Pden_2285
PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: atc:AGR_L_470 hypothetical protein.
 
     0.780
Pden_1896
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
  
 0.749
Pden_1901
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2179 ABC glycine betaine/L-proline tranporter, ATPase subunit, ProV.
 
     0.677
Pden_2286
PFAM: sulfatase; KEGG: rsp:RSP_0594 putative choline sulfatase.
 
   
 0.656
Pden_1900
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_2180 ABC glycine betaine/L-proline transporter, inner membrane subunit.
 
     0.583
Pden_0811
CDP-diacylglycerol-choline O-phosphatidyltransferase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
     0.518
Pden_1197
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ppu:PP_4753 N-methylproline demethylase, putative.
 
  
 0.464
Pden_3933
Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: rsp:RSP_2922 transcriptional regulator, AraC family.
  
     0.458
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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