Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
moaCGTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (157 aa)    
Predicted Functional Partners:
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
Pden_0501
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: bmb:BruAb2_0726 MogA, molybdenum cofactor biosynthesis protein.
  
 0.998
Pden_2340
PFAM: molybdopterin biosynthesis MoaE; KEGG: sit:TM1040_3633 molybdopterin biosynthesis MoaE.
 
 
 0.998
Pden_2141
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.967
Pden_2341
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: sit:TM1040_3632 molybdopterin converting factor, subunit 1.
  
  
 0.948
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: sil:SPO2151 indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
     
 0.907
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
     
 0.877
Pden_2136
Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rsp:RSP_2002 anthranilate synthase component II.
     
 0.874
Pden_3400
Molybdenum cofactor synthesis domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.871
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
       0.848
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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