Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pden_2148PFAM: Auxin Efflux Carrier; KEGG: rsp:RSP_0677 putative malonate transporter, MdcF, AEC family. (314 aa)    
Predicted Functional Partners:
Pden_2145
KEGG: rsp:RSP_0674 DNA polymerase III subunit delta.
 
     0.858
Pden_2146
TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; amidohydrolase 2; KEGG: rsp:RSP_0675 putative TatD-related deoxyribonuclease.
       0.855
Pden_2147
PFAM: beta-lactamase domain protein; KEGG: rsp:RSP_0676 PhnP-like protein.
       0.855
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.838
Pden_2143
Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: rsp:RSP_0550 putative D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
    0.826
Pden_0848
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rsp:RSP_1217 phosphate acetyltransferase.
  
  
 0.667
Pden_2224
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rsp:RSP_1593 phosphate acetyltransferase.
  
  
 0.667
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.471
Pden_3795
PFAM: polysaccharide deacetylase; KEGG: sil:SPO0872 polysaccharide deacetylase family protein.
 
    0.409
Pden_2206
PFAM: protein of unknown function DUF1150; KEGG: rsp:RSP_1573 hypothetical protein.
  
     0.400
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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