STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (343 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.964
Pden_2494
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sil:SPOA0227 nitrite reductase heme biosynthesis J protein.
  
 
 0.957
Pden_0001
PFAM: conserved hypothetical protein 701; KEGG: sil:SPO3893 hypothetical protein.
 
  
 0.942
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
   
 
 0.938
Pden_0616
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
 0.935
Pden_2584
KEGG: rsp:RSP_1196 SAM-dependent methyltransferase.
  
  
 0.880
Pden_2585
KEGG: rsp:RSP_1195 competence protein F.
       0.747
Pden_2586
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
     
 0.732
Pden_2587
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sil:SPO0069 hydrolase, carbon-nitrogen family.
   
 
 0.721
Pden_1752
PFAM: coproporphyrinogen III oxidase; KEGG: rsp:RSP_0682 coproporphyrinogen III oxidase.
 
   
 0.720
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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