STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_2816TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN; KEGG: rde:RD1_0088 ribonuclease BN, putative. (293 aa)    
Predicted Functional Partners:
Pden_2817
PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: pae:PA2722 hypothetical protein.
       0.663
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
     
 0.633
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.581
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
     
 0.575
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
       0.575
Pden_3341
TIGRFAM: arsenate reductase; PFAM: low molecular weight phosphotyrosine protein phosphatase; arsenate reductase and related; KEGG: nwi:Nwi_3124 low molecular weight phosphotyrosine protein phosphatase; Belongs to the ArsC family.
  
  
 0.454
Pden_1551
PFAM: protein of unknown function DUF481; KEGG: rsp:RSP_0753 salt-stress induced outer membrane protein.
     
 0.452
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.423
Pden_2188
PFAM: protein of unknown function DUF808; KEGG: jan:Jann_1699 protein of unknown function DUF808.
   
    0.416
Pden_2954
PFAM: protein of unknown function UPF0118; KEGG: jan:Jann_2214 protein of unknown function UPF0118.
 
  
 0.412
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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