Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pden_2829KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (820 aa)    
Predicted Functional Partners:
Pden_2830
PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit.
 
 0.999
Pden_2827
TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sme:SMa0007 probable FdoI formate dehydrogenase-O,gamma subunit.
 
 
 0.998
Pden_2828
TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sme:SMa0005 probable FdoH formate dehydrogenase-O, beta subunit.
 
 
 0.998
Pden_2854
KEGG: sme:SMc03086 putative NAD-dependent formate dehydrogenase delta subunit protein.
  
 0.985
Pden_2858
PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; KEGG: gbe:GbCGDNIH1_1932 NAD-dependent formate dehydrogenase gamma subunit (FdsG).
  
 0.982
Pden_2857
PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rsp:RSP_1079 NAD dependent formate dehydrogenase, beta subunit (51 kDa).
  
 0.970
fdhE
Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.951
Pden_2825
TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: sme:SMa0015 SelB selenocysteine-specific elongation factor.
 
   
 0.930
Pden_1186
Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein.
    
 0.905
fghA
Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (Probable).
    
  0.904
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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