STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_3094PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: rsp:RSP_0492 hydrogenase small subunit. (329 aa)    
Predicted Functional Partners:
Pden_3095
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rsp:RSP_0493 hydrogenase large subunit.
 
 0.999
Pden_3098
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rsp:RSP_0496 hydrogenase protein large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 0.998
Pden_3093
KEGG: rsp:RSP_0491 hydrogen uptake histidine-kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.995
Pden_3100
TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: aeh:Mlg_2027 Ni/Fe-hydrogenase, b-type cytochrome subunit.
 
 
 0.987
Pden_3106
HupK; KEGG: rsp:RSP_0504 HupK.
 
 
 0.979
Pden_3097
KEGG: rsp:RSP_0495 hydrogenase protein small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein.
 
  
0.960
Pden_3104
PFAM: HupH hydrogenase expression protein; KEGG: rsp:RSP_0502 HupH hydrogenase expression/formation protein.
 
 
 0.942
Pden_3096
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.941
Pden_3103
PFAM: hydrogenase-1 expression HyaE; KEGG: rsp:RSP_0501 HupG hydrogenase expression/formation protein; Belongs to the HupG/HyaE family.
 
 
 0.937
Pden_3101
Hydrogenase 1 maturation peptidase HyaD, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein; KEGG: rsp:RSP_0499 HycI, hydrogenase maturation protease.
 
  
 0.924
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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