Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pden_3383PFAM: type III effector Hrp-dependent outers; KEGG: reu:Reut_A1426 type III effector Hrp-dependent outers. (419 aa)    
Predicted Functional Partners:
Pden_3382
PFAM: class II aldolase/adducin family protein; KEGG: bja:bll2927 hypothetical protein.
  
 0.989
Pden_3388
PFAM: SAF domain; KEGG: rru:Rru_A3141 homoserine dehydrogenase, NAD-binding.
 
     0.837
Pden_3385
PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: msu:MS0052 hypothetical protein.
 
     0.776
Pden_3386
PFAM: cyclase family protein; KEGG: pmu:PM1641 hypothetical Synechocystis sp.
     
 0.769
Pden_3384
TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: gka:GK1972 transporter.
       0.739
Pden_3387
TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0762 possible C4-dicarboxylate transport system, periplasmic component.
       0.704
Pden_3899
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sit:TM1040_2765 hydroxypyruvate isomerase; Belongs to the hyi family.
 
  
 0.677
Pden_3218
PFAM: beta-lactamase domain protein; KEGG: bja:bll0351 hypothetical protein.
 
     0.576
Pden_4003
3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rsp:RSP_2846 putative 3-hydroxyisobutyrate dehydrogenase.
  
  
 0.478
Pden_3389
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sme:SMb20773 putative transcriptional regulator, GntR family protein.
 
     0.463
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.