close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_3545PFAM: regulatory protein, MarR; KEGG: mlo:mll8302 transcriptional regulator. (163 aa)    
Predicted Functional Partners:
Pden_0913
PFAM: homogentisate 1,2-dioxygenase; KEGG: sit:TM1040_2621 homogentisate 1,2-dioxygenase.
 
     0.632
Pden_3547
PFAM: homogentisate 1,2-dioxygenase; KEGG: sit:TM1040_2621 homogentisate 1,2-dioxygenase.
 
     0.632
Pden_1664
KEGG: sme:SMc03211 putative 4-hydroxyphenylpyruvate dioxygenase protein; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
    0.598
Pden_3549
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; KEGG: sme:SMc03206 maleylacetoacetate isomerase (glutathione transferase ZETA 1) protein.
 
     0.570
Pden_0174
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; KEGG: mlo:mlr1135 maleylacetoacetate isomerase.
 
     0.492
Pden_3542
PFAM: short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KEGG: bur:Bcep18194_C7123 short-chain dehydrogenase/reductase SDR.
       0.439
Pden_3543
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: bja:blr6805 putative dehydrogenase.
       0.439
Pden_3544
Hypothetical protein.
       0.439
Pden_3541
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bxe:Bxe_A1074 3-oxoacyl-(acyl-carrier-protein) reductase.
       0.420
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.