Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pden_3583PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sme:SMc00778 putative oxidoreductase protein. (279 aa)    
Predicted Functional Partners:
Pden_3584
TIGRFAM: FAD-linked oxidoreductase; PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00779 putative FAD-dependent oxidoreductase protein.
   
   0.703
Pden_3582
PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2; KEGG: sme:SMc01630 putative transcription regulator protein.
 
     0.613
Pden_2547
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rsp:RSP_1694 probable short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.558
Pden_3585
PFAM: Ethanolamine utilisation protein, EutH; KEGG: pfl:PFL_5470 ethanolamine utilization protein EutH.
       0.517
Pden_0836
PFAM: beta-ketoacyl synthase; Thioesterase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; phosphopantetheine-binding; KR; KEGG: sil:SPO0849 non-ribosomal peptide synthase.
  
 
 0.484
Pden_3714
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_2453 putative oxidoreductase (NAD/NADP dependent).
 
    0.417
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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