node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_2086 | Pden_3618 | Pden_2086 | Pden_3618 | RNA polymerase, sigma 32 subunit, RpoH; PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor. | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | 0.583 |
Pden_2086 | polA | Pden_2086 | Pden_1853 | RNA polymerase, sigma 32 subunit, RpoH; PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.811 |
Pden_2086 | rnhA | Pden_2086 | Pden_3617 | RNA polymerase, sigma 32 subunit, RpoH; PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.554 |
Pden_2086 | topA | Pden_2086 | Pden_0659 | RNA polymerase, sigma 32 subunit, RpoH; PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.676 |
Pden_3616 | Pden_3618 | Pden_3616 | Pden_3618 | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | 0.783 |
Pden_3616 | ispH | Pden_3616 | Pden_3619 | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.721 |
Pden_3616 | rnhA | Pden_3616 | Pden_3617 | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.868 |
Pden_3618 | Pden_2086 | Pden_3618 | Pden_2086 | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | RNA polymerase, sigma 32 subunit, RpoH; PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor. | 0.583 |
Pden_3618 | Pden_3616 | Pden_3618 | Pden_3616 | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | 0.783 |
Pden_3618 | ispH | Pden_3618 | Pden_3619 | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.551 |
Pden_3618 | rnhA | Pden_3618 | Pden_3617 | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.791 |
Pden_3806 | polA | Pden_3806 | Pden_1853 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.703 |
Pden_3806 | rnhA | Pden_3806 | Pden_3617 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.580 |
Pden_3806 | topA | Pden_3806 | Pden_0659 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.573 |
dnaQ | polA | Pden_2815 | Pden_1853 | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.593 |
dnaQ | rnhA | Pden_2815 | Pden_3617 | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.918 |
ispH | Pden_3616 | Pden_3619 | Pden_3616 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | 0.721 |
ispH | Pden_3618 | Pden_3619 | Pden_3618 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein. | 0.551 |
ispH | rnhA | Pden_3619 | Pden_3617 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.730 |
polA | Pden_2086 | Pden_1853 | Pden_2086 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RNA polymerase, sigma 32 subunit, RpoH; PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor. | 0.811 |