Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysSKEGG: sit:TM1040_1153 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa)    
Predicted Functional Partners:
Pden_2885
KEGG: rsp:RSP_2481 serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein.
 
  
 0.862
Pden_3861
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rsp:RSP_2147 O-acetylserine (thiol)-lyase, cysteine synthase.
  
 
 0.852
thrS
Ser-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
 
  
 0.848
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
  
 0.815
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: rsp:RSP_0840 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.813
hisS
PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; KEGG: sil:SPO0667 histidyl-tRNA synthetase.
  
 
 0.806
Pden_4062
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: jan:Jann_1959 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.767
Pden_4061
KEGG: sil:SPO2129 hypothetical protein.
       0.732
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
  
 
 0.704
Pden_1293
KEGG: mca:MCA1436 serine acetyltransferase CysE, putative.
  
  
 0.693
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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