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ileS protein (Shewanella putrefaciens) - STRING interaction network
"ileS" - Isoleucine--tRNA ligase in Shewanella putrefaciens
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ileSIsoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily (940 aa)    
Predicted Functional Partners:
ABP74788.1
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family (171 aa)
 
   
  0.980
ABP74786.1
KEGG- she-Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM- riboflavin biosynthesis protein RibF; PFAM- Riboflavin kinase / FAD synthetase; Belongs to the ribF family (311 aa)
 
   
  0.968
pheT
KEGG- she-Shewmr4_1809 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM- phenylalanyl-tRNA synthetase, beta subunit (795 aa)
 
 
  0.966
ABP74789.1
Peptidyl-prolyl cis-trans isomerase; KEGG- shm-Shewmr7_3037 peptidylprolyl isomerase, FKBP-type (140 aa)
 
      0.960
alaS
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (892 aa)
 
 
  0.935
leuS
Leucine--tRNA ligase; TIGRFAM- leucyl-tRNA synthetase; KEGG- son-SO1174 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (859 aa)
 
 
0.928
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as ’pretransfer’ editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated ’posttransfer’ editing and involves deacy [...] (571 aa)
   
 
  0.927
lysS
Lysine--tRNA ligase; TIGRFAM- lysyl-tRNA synthetase; PFAM- tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG- shm-Shewmr7_3196 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family (500 aa)
   
 
  0.922
argS
Arginine--tRNA ligase; KEGG- shm-Shewmr7_0456 arginyl-tRNA synthetase; TIGRFAM- arginyl-tRNA synthetase (581 aa)
   
 
  0.890
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis; Belongs to the IspH family (318 aa)
   
   
  0.889
Your Current Organism:
Shewanella putrefaciens
NCBI taxonomy Id: 319224
Other names: S. putrefaciens CN-32, Shewanella putrefaciens, Shewanella putrefaciens CN-32, Shewanella putrefaciens str. CN-32, Shewanella putrefaciens strain CN-32
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