node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP74346.1 | ABP74882.1 | Sputcn32_0615 | Sputcn32_1154 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.734 |
ABP74346.1 | ABP76010.1 | Sputcn32_0615 | Sputcn32_2289 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family. | 0.722 |
ABP74346.1 | ABP76101.1 | Sputcn32_0615 | Sputcn32_2380 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | PFAM: protein of unknown function DUF412; KEGG: shm:Shewmr7_1559 protein of unknown function DUF412. | 0.761 |
ABP74346.1 | ABP76547.1 | Sputcn32_0615 | Sputcn32_2828 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | TPR repeat-containing protein; May be involved in cell division. | 0.760 |
ABP74346.1 | ABP77411.1 | Sputcn32_0615 | Sputcn32_3703 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | KEGG: she:Shewmr4_3695 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | 0.692 |
ABP74346.1 | mutH | Sputcn32_0615 | Sputcn32_1141 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | DNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | 0.749 |
ABP74346.1 | proQ | Sputcn32_0615 | Sputcn32_2203 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.738 |
ABP74346.1 | rraB | Sputcn32_0615 | Sputcn32_3307 | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.772 |
ABP74882.1 | ABP74346.1 | Sputcn32_1154 | Sputcn32_0615 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.734 |
ABP74882.1 | ABP76010.1 | Sputcn32_1154 | Sputcn32_2289 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family. | 0.716 |
ABP74882.1 | ABP76101.1 | Sputcn32_1154 | Sputcn32_2380 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | PFAM: protein of unknown function DUF412; KEGG: shm:Shewmr7_1559 protein of unknown function DUF412. | 0.765 |
ABP74882.1 | ABP76547.1 | Sputcn32_1154 | Sputcn32_2828 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | TPR repeat-containing protein; May be involved in cell division. | 0.789 |
ABP74882.1 | ABP77411.1 | Sputcn32_1154 | Sputcn32_3703 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | KEGG: she:Shewmr4_3695 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. | 0.486 |
ABP74882.1 | mutH | Sputcn32_1154 | Sputcn32_1141 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | DNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | 0.729 |
ABP74882.1 | proQ | Sputcn32_1154 | Sputcn32_2203 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.737 |
ABP74882.1 | rraB | Sputcn32_1154 | Sputcn32_3307 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.767 |
ABP76010.1 | ABP74346.1 | Sputcn32_2289 | Sputcn32_0615 | PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.722 |
ABP76010.1 | ABP74882.1 | Sputcn32_2289 | Sputcn32_1154 | PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.716 |
ABP76010.1 | ABP76101.1 | Sputcn32_2289 | Sputcn32_2380 | PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family. | PFAM: protein of unknown function DUF412; KEGG: shm:Shewmr7_1559 protein of unknown function DUF412. | 0.747 |
ABP76010.1 | ABP76547.1 | Sputcn32_2289 | Sputcn32_2828 | PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family. | TPR repeat-containing protein; May be involved in cell division. | 0.745 |