Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABP75723.1PFAM: DsrE family protein; KEGG: shm:Shewmr7_2004 DsrE family protein. (129 aa)    
Predicted Functional Partners:
ABP75724.1
PFAM: DsrE family protein; KEGG: shm:Shewmr7_2005 DsrE family protein; Belongs to the DsrF/TusC family.
 
 0.999
ABP75725.1
PFAM: DsrH family protein; KEGG: son:SO2378 putative uncharacterized protein involved in oxidation of intracellular sulfur.
 
 0.999
ABP75726.1
DsrC family protein; Part of a sulfur-relay system.
 
 
 0.999
tusA
SirA family protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
 
 
 0.989
ABP75421.1
PFAM: SirA family protein; KEGG: shm:Shewmr7_2418 SirA family protein; Belongs to the sulfur carrier protein TusA family.
 
 
 0.986
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
    
 0.889
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
    
 0.876
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
    
 0.865
ABP74569.1
Cysteine desulfuration protein SufE; PFAM: Fe-S metabolism associated SufE; KEGG: she:Shewmr4_3132 Fe-S metabolism associated SufE.
     
 0.818
ABP75648.1
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: son:SO2442 thiS protein, putative.
     
  0.770
Your Current Organism:
Shewanella putrefaciens
NCBI taxonomy Id: 319224
Other names: S. putrefaciens CN-32, Shewanella putrefaciens CN-32, Shewanella putrefaciens str. CN-32, Shewanella putrefaciens strain CN-32
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