node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Plut_0366 | Plut_0726 | Plut_0366 | Plut_0726 | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | Deoxycytidylate deaminase, putative. | 0.911 |
Plut_0366 | dut | Plut_0366 | Plut_1418 | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.925 |
Plut_0366 | surE | Plut_0366 | Plut_0361 | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Plut_0366 | tmk | Plut_0366 | Plut_1310 | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.925 |
Plut_0577 | dut | Plut_0577 | Plut_1418 | Ribonucleotide reductase family protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.778 |
Plut_0577 | ndk | Plut_0577 | Plut_0229 | Ribonucleotide reductase family protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.915 |
Plut_0577 | polA | Plut_0577 | Plut_1645 | Ribonucleotide reductase family protein. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.661 |
Plut_0577 | tmk | Plut_0577 | Plut_1310 | Ribonucleotide reductase family protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.935 |
Plut_0726 | Plut_0366 | Plut_0726 | Plut_0366 | Deoxycytidylate deaminase, putative. | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.911 |
Plut_0726 | dut | Plut_0726 | Plut_1418 | Deoxycytidylate deaminase, putative. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.938 |
Plut_0726 | surE | Plut_0726 | Plut_0361 | Deoxycytidylate deaminase, putative. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Plut_0726 | tmk | Plut_0726 | Plut_1310 | Deoxycytidylate deaminase, putative. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.925 |
Plut_1307 | Plut_1308 | Plut_1307 | Plut_1308 | Conserved hypothetical protein. | Amino acid/polyamine/organocation transporter, APC superfamily; TC 2.A.3. | 0.642 |
Plut_1307 | Plut_1309 | Plut_1307 | Plut_1309 | Conserved hypothetical protein. | Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.642 |
Plut_1307 | tmk | Plut_1307 | Plut_1310 | Conserved hypothetical protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.519 |
Plut_1308 | Plut_1307 | Plut_1308 | Plut_1307 | Amino acid/polyamine/organocation transporter, APC superfamily; TC 2.A.3. | Conserved hypothetical protein. | 0.642 |
Plut_1308 | Plut_1309 | Plut_1308 | Plut_1309 | Amino acid/polyamine/organocation transporter, APC superfamily; TC 2.A.3. | Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.773 |
Plut_1308 | tmk | Plut_1308 | Plut_1310 | Amino acid/polyamine/organocation transporter, APC superfamily; TC 2.A.3. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.618 |
Plut_1309 | Plut_1307 | Plut_1309 | Plut_1307 | Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Conserved hypothetical protein. | 0.642 |
Plut_1309 | Plut_1308 | Plut_1309 | Plut_1308 | Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Amino acid/polyamine/organocation transporter, APC superfamily; TC 2.A.3. | 0.773 |