STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN14635.1Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)    
Predicted Functional Partners:
ANN19150.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.693
SD37_22285
Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.663
ANN15701.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.636
ANN17635.1
Proteasome accessory factor PafA2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.634
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
    0.602
ANN22037.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.582
ANN22363.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.577
ANN15219.1
Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.538
ANN15603.1
MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.517
ANN14636.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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